ExeGi Pharma Celebrates 25th Anniversary of Landmark De Simone Formulation standard
Rockville, Md. – ExeGi Pharma, a biotechnology company specializing in live biotherapeutics, today announced the 25th anniversary of the De Simone Formulation, a high potency probiotic blend that has transformed the landscape of gastrointestinal care. The formulation first gained clinical prominence in August 2000, when Professor Paolo Gionchetti and colleagues published a landmark study demonstrating that this probiotic benefits in a serious chronic inflammatory gastrointestinal disorder called pouchitis.1 That 2000 study – a breakthrough for the probiotic industry – showed significant benefits vs placebo and underscored the formulation’s potential to alter the course of serious gastrointestinal conditions. It also marked one of the first times a probiotic therapy proved superior to placebo in a rigorous clinical trial which was published in ...
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